NeuroSearch drug trial results cheer stock market  

2008.08.13
NeuroSearch's share price jumps 8% on positive final results of a metabolic study of obesity & type 2 diabetes drug candidate tesofensine
Danish biopharmaceutical company NeuroSearch has announced in a press release the final results of a human metabolic study of its obesity and type 2 diabetes drug candidate tesofensine. The study supports tesofensine's potential as an effective new treatment for these conditions, and shows that weight reduction is obtained through both appetite suppression and a favourable impact on energy and fat metabolism.
 
The OMX Nordic Exchange Copenhagen responded warmly to the news on Monday, with NeuroSearch's share price leaping 8.2%.
 
The study involved 32 overweight and obese subjects being treated for 14 days with either tesofensine or placebo. The study found that tesofensine, which belongs to a category of drugs called monoamine reuptake inhibitors, reduces appetite sensations, reduces fat tissue, improves insulin sensitivity and increases energy expenditure at rest.
 
NeuroSearch develops novel drugs based on a broad and well-established drug discovery platform focusing on ion channels and CNS disorders. A substantial part of the company’s activities are partner financed through a broad alliance with GlaxoSmithKline and collaborations with Abbott and Astellas. The drug pipeline comprises 14 clinical development (Phase I-III) programmes, including a Phase III drug candidate in Huntington's disease.
 
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